4 The probability of contracting Lyme disease after a tick bite in an area of endemic disease has been reported to range from 0.012 to 0.05 (pooled estimate from four studies, 0.027 95 percent confidence interval, 0.013 to 0.049). 1 The primary vectors are Ixodes dammini in the northeast and midwestern United States 2, 3 and I. Spread to humans by infected ticks, it is the most common vector-borne illness in the United States. LYME disease is a multisystem disorder caused by the spirochete Borrelia burgdorferi. When the probability of infection after a tick bite is less than 0.01, empirical therapy is not warranted. burgdorferi infection after a bite is 0.036 or higher, and this treatment may be preferred when the probability of infection ranges from 0.01 to 0.035. Conclusions.Įmpirical treatment of patients with tick bites is indicated when the probability of B.
For probabilities of infection below 0.036, empirical therapy prevents most major complications, sequelae, and adverse events, but it incurs additional minor complications, especially as the probability of infection falls below 0.01. Results.Įmpirical treatment is the least expensive strategy and results in the fewest cases of Lyme disease and the fewest complications when the probability of Borrelia burgdorferi infection after a tick bite is 0.036 or higher. We used decision analysis to evaluate the outcomes, costs, and cost effectiveness of three alternative strategies to treat patients bitten by ixodes ticks in areas of endemic Lyme disease: empirically treat all patients with two weeks of doxycycline, treat only patients in whom erythema migrans develops, and treat only patients with erythema migrans or a positive serologic test for Lyme disease one month after exposure. Early treatment with oral antibiotics prevents most complications of Lyme disease, but antibiotics are generally not prescribed until rash or other symptoms develop. In areas of endemic disease, the probability of Lyme disease after a tick bite ranges from about 0.012 to 0.05. The most trusted, influential source of new medical knowledge and clinical best practices in the world.
#Infected tick bite license#
Information and tools for librarians about site license offerings. Valuable tools for building a rewarding career in health care. The authorized source of trusted medical research and education for the Chinese-language medical community.
The most advanced way to teach, practice, and assess clinical reasoning skills. Information, resources, and support needed to approach rotations - and life as a resident. The most effective and engaging way for clinicians to learn, improve their practice, and prepare for board exams. NEW! Peer-reviewed journal featuring in-depth articles to accelerate the transformation of health care delivery.Ĭoncise summaries and expert physician commentary that busy clinicians need to enhance patient care.
#Infected tick bite trial#
NEW! A digital journal for innovative original research and fresh, bold ideas in clinical trial design and clinical decision-making.
0 kommentar(er)
